SCHEMBL9975563

SCHEMBL9975563

COC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.50
EPHX2 P34913 4/20 0.45
ALOX5 P09917 2/20 0.42
OXER1 Q8TDS5 1/20 0.42
NR1I2 O75469 1/20 0.41
PGR P06401 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
PTGS2 P35354 1/20 0.41
PDE4D Q08499 1/20 0.41
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26696497 0.81 EPHX2 (0.55) EPHX2CA12CA2CA7CA9
SCHEMBL9245622 0.78 EPHX2 (0.58) EPHX2CA12CA2CA7CA9
SCHEMBL9975557 0.78 CNR2 (0.60) FAAH
SCHEMBL1758641 0.77 EPHX2 (0.50) EPHX2CA12CA2CA7CA9
SCHEMBL18102165 0.76 MGLL (0.55) FAAHALOX5OXER1NR1I2PGR
SCHEMBL17399522 0.74 ADORA3 (0.54) FAAHEPHX2ALOX5OXER1NR1I2
SCHEMBL19387708 0.74 ADORA3 (0.54) FAAHEPHX2ALOX5OXER1NR1I2
SCHEMBL2425661 0.73 TSHR (0.67) EPHX2ALOX5OXER1NR1I2PGR
SCHEMBL2425660 0.73 TSHR (0.67) EPHX2ALOX5OXER1NR1I2PGR
SCHEMBL15385465 0.73 MGLL (0.56) FAAHEPHX2ALOX5OXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202893-B2 Cannabinergic lipid ligands UNIVERSITY OF CONNECTICUT (US) 2012-06-19 US disclosed
US-8202893-B2 Cannabinergic lipid ligands UNIVERSITY OF CONNECTICUT (US) 2012-06-19 US disclosed
US-20090163557-A1 Cannabinergic Lipid Ligands NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-06-25 US disclosed
US-20090163557-A1 Cannabinergic Lipid Ligands NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163557-A1 Cannabinergic Lipid Ligands FAAH, FAAH2, CNR2 FAAH 1/4885EPHX2 681/4885ALOX5 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.