Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382741 | 0.94 | ADRA2C (0.32) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL10381889 | 0.94 | ADRA2C (0.32) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL19397886 | 0.86 | ADRA2C (0.34) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL10382029 | 0.85 | RAF1 (0.32) | NR1I2 | |
| SCHEMBL9941462 | 0.85 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL9941479 | 0.84 | NR1I2 (0.40) | NR1I2 | |
| SCHEMBL10382630 | 0.84 | RAF1 (0.41) | — | |
| SCHEMBL9975714 | 0.83 | NR1I2 (0.46) | NR1I2 | |
| SCHEMBL9941407 | 0.83 | NR1I2 (0.46) | NR1I2 | |
| SCHEMBL10381852 | 0.82 | ADRA2C (0.31) | ADRA2CPTGS2HRH1HTR3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120183496-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2012083105-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183496-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | POLR2A, POLR2B, POLR2E | ADRA2C 1014/4885PTGS2 2342/4885HRH1 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.