Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366120 | 0.82 | ALDH1A1 (0.84) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL12844631 | 0.79 | RECQL (0.83) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL10366121 | 0.78 | RECQL (0.75) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL15807121 | 0.75 | RECQL (0.76) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL15865967 | 0.74 | KDM4E (0.76) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL16199688 | 0.71 | RECQL (0.59) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL9975826 | 0.71 | RECQL (0.73) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL4477888 | 0.71 | RECQL (0.73) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL1464710 | 0.71 | RECQL (0.73) | ALDH1A1HTTRECQLKDM4ETSHR | |
| SCHEMBL259219 | 0.71 | RECQL (0.73) | ALDH1A1HTTRECQLKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120183496-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2012083105-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183496-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | POLR2A, POLR2B, POLR2E | ALDH1A1 577/4885HTT 4482/4885RECQL 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.