SCHEMBL9975945

SCHEMBL9975945

CC1(C)CCCC2(C)c3cccc(O)c3CCC12

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.64
USP2 O75604 4/20 0.64
TP53 P04637 4/20 0.64
MAPT P10636 4/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
MAPK1 P28482 2/20 0.64
HSP90AA1 P07900 1/20 0.64
KDM4E B2RXH2 1/20 0.64
CETP P11597 5/20 0.53
CYP19A1 P11511 1/20 0.48
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
PIK3CA P42336 3/20 0.42
PIK3CG P48736 3/20 0.42
PIK3CB P42338 1/20 0.42
NR1H2 P55055 3/20 0.41
NR1H3 Q13133 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30482554 0.81 CYP3A4 (0.62) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL16238019 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL30105648 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL31121504 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL1839596 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL285501 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL13423504 0.79 CYP3A4 (1.00) CYP3A4USP2TP53MAPTMEN1
SCHEMBL20970940 0.72 USP2 (0.82) CYP3A4USP2TP53MAPTMEN1
SCHEMBL6282209 0.71 SOD1 (0.66) CYP3A4USP2TP53MAPTMEN1
Totarol SCHEMBL31287563 0.71 CYP3A4 (0.74) CYP3A4USP2TP53MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140363864-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1,4-CYCLOHEXANEDIMETHANOL GENOMATICA, INC. (US) 2014-12-11 US disclosed
US-20140363864-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1,4-CYCLOHEXANEDIMETHANOL GENOMATICA, INC. (US) 2014-12-11 US disclosed
US-20120156740-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1,4-CYCLOHEXANEDIMETHANOL GENOMATICA, INC. (US) 2012-06-21 US disclosed
US-20120156740-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF 1,4-CYCLOHEXANEDIMETHANOL GENOMATICA, INC. (US) 2012-06-21 US disclosed