Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976083 | 0.86 | MAOB (0.67) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL11866217 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL8869846 | 0.79 | ALDH1A1 (0.60) | ACHEALDH1A1HPGDKDM4EMAPT | |
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.79 | MAPT (1.00) | ACHEALDH1A1HPGDKDM4EMAPT | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.79 | MAPT (1.00) | ACHEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL266614 | 0.78 | MAPT (0.63) | ACHEALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL2161251 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL29619913 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL18397791 | 0.78 | PPARG (0.65) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL21623589 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994079-A | Method for synthesizing chromone, 1-thiochromone and gamma-pyrone compounds | 中国科学院上海药物研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-3597187-A1 | BRAG2 INHIBITORS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-01-22 | — | — | EP | disclosed |
| US-8546397-B2 | DNA methylation inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546397-B2 | DNA methylation inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2012087889-A2 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | MECP2, DNMT1, DNMT3B | ACHE 1560/4885ALDH1A1 2789/4885HPGD 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.