Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | TNKS | O95271 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976084 | 0.86 | ACHE (0.68) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1500139 | 0.83 | MAOB (0.67) | MAOBKDM4EALDH1A1EPHX2TNKS | |
| SCHEMBL11179993 | 0.81 | KDM4E (0.65) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| 4,7-Dimethoxyflavone SCHEMBL3470601 | 0.80 | MAOB (1.00) | MAOBKDM4EALDH1A1TNKSCYP19A1 | |
| SCHEMBL11511009 | 0.79 | MAOB (0.61) | MAOBKDM4EALDH1A1EPHX2TNKS | |
| SCHEMBL7327128 | 0.79 | MAOB (0.61) | MAOBKDM4EALDH1A1EPHX2TNKS | |
| SCHEMBL11511395 | 0.79 | KDM4E (0.72) | MAOBKDM4EALDH1A1EPHX2TNKS | |
| SCHEMBL7366672 | 0.79 | SIGMAR1 (0.49) | MAOBKDM4EALDH1A1HPGDGAA | |
| 2,7-Dimethylchromone SCHEMBL7600130 | 0.78 | ALDH1A1 (0.64) | MAOBKDM4EALDH1A1TNKSHPGD | |
| SCHEMBL3661536 | 0.78 | NPC1 (0.83) | MAOBKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409624-B | Chromone compound separated from trichoderma harzianum and preparation method and application thereof | 海南大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-114409624-B | Chromone compound separated from trichoderma harzianum and preparation method and application thereof | 海南大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-114409624-A | Chromone compound separated from trichoderma harzianum and preparation method and application thereof | 海南大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409624-A | Chromone compound separated from trichoderma harzianum and preparation method and application thereof | 海南大学 | 2022-04-29 | — | — | CN | disclosed |
| US-8546397-B2 | DNA methylation inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546397-B2 | DNA methylation inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2012087889-A2 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157465-A1 | DNA METHYLATION INHIBITORS | MECP2, DNMT1, DNMT3B | MAOB 1781/4885KDM4E 427/4885ALDH1A1 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.