⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976547 | 0.78 | AKR1B1 (0.33) | — | |
| SCHEMBL9976572 | 0.77 | LTA4H (0.42) | — | |
| SCHEMBL15672434 | 0.75 | KDM4E (0.40) | — | |
| SCHEMBL9976553 | 0.75 | LTA4H (0.53) | — | |
| SCHEMBL9976543 | 0.74 | KDM4E (0.42) | — | |
| SCHEMBL9976578 | 0.73 | ACACA (0.33) | — | |
| SCHEMBL498510 | 0.72 | APP (0.33) | — | |
| SCHEMBL21156754 | 0.72 | APP (0.33) | — | |
| SCHEMBL24597091 | 0.71 | DPP4 (0.47) | — | |
| SCHEMBL9976540 | 0.70 | LTA4H (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710246-B2 | Substituted thiophene pentamers | BIOCHROMIX NEWCO AB (SE) | 2014-04-29 | — | — | US | disclosed |
| US-8710246-B2 | Substituted thiophene pentamers | BIOCHROMIX NEWCO AB (SE) | 2014-04-29 | — | — | US | disclosed |
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | BIOCHROMIX PHARMA AB | 2012-06-21 | — | — | US | disclosed |
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | BIOCHROMIX PHARMA AB | 2012-06-21 | — | — | US | disclosed |
| WO-2010044744-A1 | NOVEL THIOPHENE COMPOUNDS FOR IN VIVO IMAGING | BIOCHROMIX AB (SE) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010044743-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPHY | BIOCHROMIX PHARMA AB (SE) | 2010-04-22 | — | — | WO | disclosed |