Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965654 | 0.87 | MAPT (0.32) | PDGFRBKITTP53SMN1; SMN2MAPT | |
| SCHEMBL9965662 | 0.85 | HSD17B1 (0.33) | — | |
| SCHEMBL10002013 | 0.82 | APP (0.45) | PDGFRBKITAPPTP53RAB9A | |
| SCHEMBL13000069 | 0.82 | BCHE (0.32) | SMN1; SMN2 | |
| SCHEMBL16011190 | 0.77 | APP (0.40) | PDGFRBKITAPPTP53RAB9A | |
| SCHEMBL16011184 | 0.76 | THRB (0.38) | APPSMN1; SMN2MAPTALOX15OPRD1 | |
| SCHEMBL21291329 | 0.76 | THRB (0.38) | APPSMN1; SMN2MAPTALOX15OPRD1 | |
| SCHEMBL14838429 | 0.76 | THRB (0.38) | APPSMN1; SMN2MAPTALOX15OPRD1 | |
| SCHEMBL16024128 | 0.76 | THRB (0.38) | APPSMN1; SMN2MAPTALOX15OPRD1 | |
| SCHEMBL14838376 | 0.76 | THRB (0.38) | APPSMN1; SMN2MAPTALOX15OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079160-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2012-06-21 | — | — | WO | disclosed |