Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9977620 | 0.87 | PDGFRB (0.33) | MAPTTP53SMN1; SMN2PDGFRBKIT | |
| SCHEMBL12999573 | 0.84 | HSD17B1 (0.31) | — | |
| SCHEMBL9965656 | 0.84 | EP300 (0.31) | — | |
| SCHEMBL10035902 | 0.80 | ALOX5 (0.37) | MAPTTP53SMN1; SMN2PDGFRBKIT | |
| SCHEMBL10002013 | 0.79 | APP (0.45) | MAPTTP53SMN1; SMN2PDGFRBKIT | |
| SCHEMBL16021760 | 0.77 | OPRD1 (0.41) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL16011190 | 0.74 | APP (0.40) | MAPTTP53SMN1; SMN2PDGFRBKIT | |
| SCHEMBL14838430 | 0.73 | MAOA (0.35) | MAPTTHRB | |
| SCHEMBL14838514 | 0.72 | OPRD1 (0.39) | MAPTTP53SMN1; SMN2PDGFRBKIT | |
| SCHEMBL9965662 | 0.72 | HSD17B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079159-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS INC. (CA) | 2012-06-21 | — | — | WO | disclosed |