Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011190 | 0.94 | APP (0.40) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL14838514 | 0.91 | OPRD1 (0.39) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL14838376 | 0.90 | THRB (0.38) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL16011184 | 0.90 | THRB (0.38) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL21291329 | 0.90 | THRB (0.38) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL14838429 | 0.90 | THRB (0.38) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL16024128 | 0.90 | THRB (0.38) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL16021760 | 0.90 | OPRD1 (0.41) | APPOPRD1ESR1ESR2IKBKB | |
| SCHEMBL14838263 | 0.88 | TRPA1 (0.47) | APPESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL10035902 | 0.88 | ALOX5 (0.37) | APPOPRD1ESR1ESR2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| EP-2652547-B1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MAT INC (CA) | 2019-10-23 | — | — | EP | disclosed |
| US-10416521-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2019-09-17 | — | — | US | disclosed |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | SWITCH MATERIALS, INC. (CA) | 2019-04-09 | — | — | US | disclosed |
| US-20180210308-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SOLUTIA CANADA INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| US-20180210308-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SOLUTIA CANADA INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| US-20170108753-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SOLUTIA CANADA INC. (CA) | 2017-04-20 | — | — | US | disclosed |
| US-20170108753-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SOLUTIA CANADA INC. (CA) | 2017-04-20 | — | — | US | disclosed |
| US-9568799-B2 | Variable transmittance optical filter with substantially co-planar electrode system | SWITCH MATERIALS, INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| US-9568799-B2 | Variable transmittance optical filter with substantially co-planar electrode system | SWITCH MATERIALS, INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| US-20130278989-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS, INC. (CA) | 2013-10-24 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130208333-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2013-08-15 | — | — | US | disclosed |
| US-20130208333-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2013-08-15 | — | — | US | disclosed |
| US-8441707-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2013-05-14 | — | — | US | disclosed |
| US-8441707-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2013-05-14 | — | — | US | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| US-20120044560-A9 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20100315693-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | APP 3371/4885OPRD1 768/4885ESR1 1818/4885 |
| US-20170108753-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | HCN2, HCN4, HCN1 | APP 1934/4885OPRD1 3600/4885ESR1 867/4885 |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | HCN2, HCN4, HCN1 | APP 1934/4885OPRD1 3600/4885ESR1 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.