SCHEMBL997789

SCHEMBL997789

Cc1ccc(-c2ccc(N(c3ccc(-c4ccc(C)cc4)cc3)c3cc(N(c4ccc(-c5ccc(C)cc5)cc4)c4ccc(-c5ccc(C)cc5)cc4)cc(N(c4ccc(-c5ccc(C)cc5)cc4)c4ccc(-c5ccc(C)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MCL1 Q07820 1/20 0.35
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34
NOTUM Q6P988 1/20 0.34
ICMT O60725 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
KIF11 P52732 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2438799 1.00 ALDH1A1 (0.46) ALDH1A1TSHRACHETDP1MCL1
SCHEMBL2149664 1.00 ALDH1A1 (0.46) ALDH1A1TSHRACHETDP1MCL1
SCHEMBL2439851 1.00 ALDH1A1 (0.46) ALDH1A1TSHRACHETDP1MCL1
SCHEMBL14016103 0.95 ALDH1A1 (0.42) ALDH1A1TSHRACHETDP1MCL1
SCHEMBL133517 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A
SCHEMBL8927323 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A
SCHEMBL6950285 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A
SCHEMBL17358866 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A
SCHEMBL16406860 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A
SCHEMBL13020815 0.92 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461572-B2 Organic luminescent device and manufacturing method thereof DENSO CORPORATION (JP) 2013-06-11 US disclosed
EP-2056371-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT BANDO CHEMICAL IND (JP) 2012-09-26 EP disclosed
US-8043723-B2 Organic EL device with organic layer including starburst compound DENSO CORPORATION (JP) 2011-10-25 US disclosed
US-8043725-B2 Organic electroluminescence element BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-25 US disclosed
US-8043725-B2 Organic electroluminescence element BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-25 US disclosed
US-8029920-B2 1,3,5-tris(diarylamino)benzenes and use thereof BANDO CHEMICAL INDUSTRIES, LTD (JP) 2011-10-04 US disclosed
US-8029920-B2 1,3,5-tris(diarylamino)benzenes and use thereof BANDO CHEMICAL INDUSTRIES, LTD (JP) 2011-10-04 US disclosed
US-8029920-B2 1,3,5-tris(diarylamino)benzenes and use thereof BANDO CHEMICAL INDUSTRIES, LTD (JP) 2011-10-04 US disclosed
EP-1995235-B1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL IND (JP) 2011-09-14 EP disclosed
EP-1995235-B1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL IND (JP) 2011-09-14 EP disclosed
US-20100006828-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT BANDO CHEMICAL INDUSTRIAL, LTD. (JP) 2010-01-14 US disclosed
EP-2056371-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Bando Chemical Industries, Ltd. (JP) 2009-05-06 EP disclosed
US-20090058287-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 US disclosed
US-20090058287-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 US disclosed
US-20090058287-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 US disclosed
EP-1995235-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2008-11-26 EP disclosed
EP-1995235-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2008-11-26 EP disclosed
US-7374830-B2 Organic electroluminescent device DENSO CORPORATION (JP) 2008-05-20 US disclosed
US-7374830-B2 Organic electroluminescent device DENSO CORPORATION (JP) 2008-05-20 US disclosed
US-20070224449-A1 Organic EL device DENSO CORPORATION (JP) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090058287-A1 NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF TMBIM6, TNPO1, CACNA1I ALDH1A1 2458/4885TSHR 4439/4885ACHE 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.