SCHEMBL5264547

SCHEMBL5264547

COC(=O)C(C/C=C/Cl)(C(=O)OC)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605687 1.00 MAPT (0.32) MAPTDGAT1
SCHEMBL16305496 0.89
SCHEMBL9978452 0.80 DGAT1 (0.38) DGAT1
SCHEMBL622756 0.79 GRIK1 (0.32)
SCHEMBL14425429 0.79
SCHEMBL622757 0.79 GRIK1 (0.32)
SCHEMBL28728319 0.77 MAPT (0.47) MAPTDGAT1
SCHEMBL233418 0.70 MMP8 (0.39) DGAT1
SCHEMBL14619101 0.69
SCHEMBL231232 0.67 DGAT1 (0.34) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1571138-B2 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF ASAHI GLASS CO LTD (JP) 2014-12-17 EP disclosed
WO-2012021446-A2 PROCESS FOR PREPARING ALISKIREN AND ITS INTERMEDIATES DR. REDDY'S LABORATORIES LTD. (IN) 2012-02-16 WO disclosed
US-20070191630-A1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOATE AND OPTICALLY ACTIVE FORM THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2007-08-16 US disclosed
US-20070191630-A1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOATE AND OPTICALLY ACTIVE FORM THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2007-08-16 US disclosed
US-20070191630-A1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOATE AND OPTICALLY ACTIVE FORM THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2007-08-16 US disclosed
EP-1801094-A1 METHOD FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOATE AND OPTICALLY ACTIVE SUBSTANCE THEREOF Asahi Glass Company, Limited (JP) 2007-06-27 EP disclosed
US-7232925-B2 Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof ASAHI GLASS COMPANY, LIMITED (JP) 2007-06-19 US disclosed
US-7232925-B2 Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof ASAHI GLASS COMPANY, LIMITED (JP) 2007-06-19 US disclosed
US-7232925-B2 Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof ASAHI GLASS COMPANY, LIMITED (JP) 2007-06-19 US disclosed
EP-1571138-B1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF ASAHI GLASS CO LTD (JP) 2007-02-28 EP disclosed
US-20050228193-A1 Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof ASAHI GLASS COMPANY LIMITED (JP) 2005-10-13 US disclosed
EP-1571138-A1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF ASAHI GLASS COMPANY LTD. (JP) 2005-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228193-A1 Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof C5, ALOX5, PTGER4 MAPT 4806/4885DGAT1 829/4885
US-20070191630-A1 PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOATE AND OPTICALLY ACTIVE FORM THEREOF ACSL4, EPB41, PLAAT4 MAPT 3732/4885DGAT1 1221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.