Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | GRN | P28799 | 6/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060290 | 0.96 | RAB9A (0.56) | RAB9AFABP4GRNSORT1DDR1 | |
| SCHEMBL11655465 | 0.87 | RAB9A (0.47) | RAB9AFABP4GRNSORT1DDR1 | |
| SCHEMBL29956823 | 0.84 | RAB9A (0.45) | RAB9AFABP4GRNSORT1DDR1 | |
| SCHEMBL9979308 | 0.84 | SMN1; SMN2 (0.48) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL5020958 | 0.84 | FABP4 (0.62) | RAB9AFABP4GRNSORT1DDR1 | |
| SCHEMBL14060193 | 0.81 | FABP4 (0.58) | RAB9AFABP4GRNSORT1DDR1 | |
| SCHEMBL4154673 | 0.81 | ALDH1A1 (0.56) | P2RX7GPR139MEN1KMT2AMAPT | |
| SCHEMBL4411412 | 0.80 | HCAR2 (0.55) | LMNAMEN1KMT2AMAPTHPGD | |
| SCHEMBL4146583 | 0.79 | MEN1 (0.69) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL10645430 | 0.79 | RAB9A (0.54) | RAB9AFABP4GRNSORT1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154842-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING | PROTEGO BIOPHARMA, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |