Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979703 | 0.91 | L3MBTL1 (0.36) | PPARDPPARAPPARGMAPTSMN1; SMN2 | |
| SCHEMBL9979617 | 0.90 | PPARD (0.46) | PPARDPPARAPPARGMAPTALOX15 | |
| SCHEMBL9979633 | 0.84 | PPARD (0.55) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL9979624 | 0.82 | PPARD (0.38) | PPARDPPARAPPARGMAPTSMN1; SMN2 | |
| SCHEMBL9979668 | 0.80 | POLB (0.43) | MAPTALOX15SMN1; SMN2HTT | |
| SCHEMBL9979531 | 0.78 | PPARD (0.42) | PPARDPPARAPPARG | |
| SCHEMBL9979498 | 0.77 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL9979618 | 0.77 | PPARD (0.44) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL9979623 | 0.77 | PPARD (0.67) | PPARDPPARAPPARGFFAR1PTGER4 | |
| SCHEMBL9979669 | 0.74 | PPARD (0.53) | PPARDPPARAPPARGFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |