Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 5/20 | 0.38 |
| ▸ | CBLB | Q13191 | 10/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979629 | 0.87 | PPARD (0.41) | UGCGCBLBCHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979551 | 0.82 | UGCG (0.45) | UGCGCBLBCHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979553 | 0.72 | UGCG (0.43) | UGCGCBLBPTGS1PTGS2 | |
| SCHEMBL9979557 | 0.72 | UGCG (0.45) | UGCGCBLBCHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979580 | 0.71 | PKM (0.41) | UGCGGRM1 | |
| SCHEMBL9979506 | 0.70 | PPARD (0.62) | — | |
| SCHEMBL9979554 | 0.69 | UGCG (0.43) | UGCGCBLBPTGS1PTGS2 | |
| SCHEMBL9979709 | 0.69 | PPARD (0.50) | UGCG | |
| SCHEMBL9979627 | 0.68 | UGCG (0.45) | UGCGCBLBCHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979608 | 0.68 | PPARD (0.50) | UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |