Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979584 | 0.94 | POLB (0.44) | PPARDMEN1KMT2APOLBMAPT | |
| SCHEMBL9979618 | 0.90 | PPARD (0.44) | PPARDPPARAMEN1KMT2APOLB | |
| SCHEMBL9979510 | 0.90 | PPARD (0.53) | PPARDPPARAMEN1KMT2APOLB | |
| SCHEMBL9979669 | 0.90 | PPARD (0.53) | PPARDPPARAMAPTFFAR1SMN1; SMN2 | |
| SCHEMBL9979640 | 0.85 | PPARD (0.51) | PPARDPPARAMEN1KMT2APOLB | |
| SCHEMBL9979633 | 0.80 | PPARD (0.55) | PPARDPPARAMAPTFFAR1SMN1; SMN2 | |
| SCHEMBL9979623 | 0.80 | PPARD (0.67) | PPARDPPARAFFAR1MAOAMAOB | |
| SCHEMBL9979668 | 0.77 | POLB (0.43) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL9979502 | 0.77 | PPARD (0.41) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL9979703 | 0.76 | L3MBTL1 (0.36) | PPARDPPARAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |