Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979510 | 0.93 | PPARD (0.53) | PPARDPPARAPPARGPOLBMEN1 | |
| SCHEMBL9979584 | 0.92 | POLB (0.44) | PPARDPOLBMEN1KMT2AMAPT | |
| SCHEMBL9979520 | 0.90 | PPARD (0.43) | PPARDPPARAPPARGPOLBMEN1 | |
| SCHEMBL9979633 | 0.90 | PPARD (0.55) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL9979703 | 0.86 | L3MBTL1 (0.36) | PPARDPPARAPPARGPOLBMEN1 | |
| SCHEMBL9979640 | 0.83 | PPARD (0.51) | PPARDPPARAPPARGPOLBMEN1 | |
| SCHEMBL9979623 | 0.82 | PPARD (0.67) | PPARDPPARAPPARGFFAR1MAOA | |
| SCHEMBL9979669 | 0.80 | PPARD (0.53) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL9979527 | 0.79 | FFAR1 (0.42) | PPARDPPARGFFAR1 | |
| SCHEMBL9979700 | 0.79 | PPARD (0.46) | PPARDPPARAPPARGPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |