Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979598 | 0.88 | LMNA (0.45) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL14578333 | 0.81 | SMN1; SMN2 (0.41) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL14578372 | 0.81 | ALDH1A1 (0.38) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL5119905 | 0.80 | ALDH1A1 (0.42) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL5119902 | 0.80 | ALDH1A1 (0.42) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL14578189 | 0.80 | NR3C1 (0.41) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL14578089 | 0.79 | LMNA (0.43) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL9979545 | 0.79 | NR3C1 (0.43) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL9979550 | 0.78 | ATM (0.55) | L3MBTL1SMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL14578373 | 0.76 | CHRM3 (0.39) | L3MBTL1CYP1A2KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |