Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578089 | 0.91 | LMNA (0.43) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14578333 | 0.90 | SMN1; SMN2 (0.41) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5119902 | 0.88 | ALDH1A1 (0.42) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5119905 | 0.88 | ALDH1A1 (0.42) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14578189 | 0.88 | NR3C1 (0.41) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14578372 | 0.88 | ALDH1A1 (0.38) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9979546 | 0.88 | L3MBTL1 (0.47) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9979545 | 0.86 | NR3C1 (0.43) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14578373 | 0.86 | CHRM3 (0.39) | LMNAALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9979664 | 0.84 | LMNA (0.45) | LMNAALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |