Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979668 | 0.91 | POLB (0.43) | MAPTALOX15SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9979617 | 0.89 | PPARD (0.46) | MAPTALOX15SMN1; SMN2TP53 | |
| SCHEMBL9979660 | 0.87 | PPARD (0.41) | MAPTALOX15SMN1; SMN2HTTFFAR1 | |
| SCHEMBL9979624 | 0.83 | PPARD (0.38) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL9979703 | 0.81 | L3MBTL1 (0.36) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL9979640 | 0.81 | PPARD (0.51) | MAPTALOX15SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9979579 | 0.75 | PPARD (0.41) | NPC1RAB9AFFAR1PKM | |
| SCHEMBL9979584 | 0.74 | POLB (0.44) | MAPTMEN1KMT2AHTTTSHR | |
| SCHEMBL9979669 | 0.72 | PPARD (0.53) | MAPTALOX15SMN1; SMN2FFAR1 | |
| SCHEMBL9979623 | 0.70 | PPARD (0.67) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |