Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979613 | 0.90 | CYP11B1 (0.33) | CYP11B1CYP11B2UGCGCHRM2CHRM4 | |
| SCHEMBL9979616 | 0.82 | FFAR4 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9979585 | 0.82 | CHRM2 (0.34) | ALDH1A1UGCGCHRM2CHRM4CHRM5 | |
| SCHEMBL9979619 | 0.79 | ITGB3 (0.35) | UGCGRORC | |
| SCHEMBL9979620 | 0.72 | ITGB3 (0.35) | UGCG | |
| SCHEMBL9979646 | 0.72 | CYP11B1 (0.40) | CYP11B1CYP11B2UGCGCMA1CBLB | |
| SCHEMBL9979691 | 0.72 | CYP11B1 (0.40) | ALDH1A1KDM4ECYP11B1CYP11B2UGCG | |
| SCHEMBL9979517 | 0.72 | FFAR4 (0.43) | — | |
| SCHEMBL9979638 | 0.71 | PPARD (0.47) | CYP11B1CYP11B2UGCG | |
| SCHEMBL9979485 | 0.71 | PPARD (0.47) | CYP11B1CYP11B2UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |