Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979585 | 0.91 | CHRM2 (0.34) | NPC1PKMRAB9AFFAR4GRM1 | |
| SCHEMBL9979619 | 0.90 | ITGB3 (0.35) | ITGB3ITGA2BFFAR4UGCGFFAR1 | |
| SCHEMBL9979517 | 0.88 | FFAR4 (0.43) | ITGB3ITGA2BFFAR4FFAR1 | |
| SCHEMBL9979613 | 0.83 | CYP11B1 (0.33) | FFAR4GRM1UGCGFFAR1 | |
| SCHEMBL9979616 | 0.82 | FFAR4 (0.38) | FFAR4FFAR1 | |
| SCHEMBL9979702 | 0.72 | ALDH1A1 (0.35) | UGCG | |
| SCHEMBL9979575 | 0.72 | PPARA (0.42) | NPC1PKMRAB9AFFAR1 | |
| SCHEMBL9979708 | 0.72 | PPARD (0.48) | UGCG | |
| SCHEMBL9979580 | 0.71 | PKM (0.41) | NPC1PKMRAB9AGRM1UGCG | |
| SCHEMBL18160779 | 0.70 | ITGB3 (0.54) | ITGB3ITGA2BFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |