Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979613 | 0.92 | CYP11B1 (0.33) | FFAR4FFAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9979517 | 0.91 | FFAR4 (0.43) | FFAR4FFAR1SIGMAR1 | |
| SCHEMBL9979585 | 0.91 | CHRM2 (0.34) | FFAR4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9979620 | 0.82 | ITGB3 (0.35) | FFAR4FFAR1 | |
| SCHEMBL9979702 | 0.82 | ALDH1A1 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9979619 | 0.82 | ITGB3 (0.35) | FFAR4FFAR1 | |
| SCHEMBL9979707 | 0.77 | PPARD (0.48) | — | |
| SCHEMBL9979513 | 0.77 | PPARD (0.48) | — | |
| SCHEMBL9979694 | 0.77 | PPARA (0.41) | LIPE | |
| SCHEMBL9979507 | 0.76 | PPARD (0.47) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |