Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10450123 | 0.96 | GPR3 (0.61) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL11940264 | 0.96 | GPR3 (0.61) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL16791290 | 0.96 | GPR3 (0.61) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL17676358 | 0.95 | GPR3 (0.55) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL17676398 | 0.95 | GPR3 (0.55) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL17904086 | 0.95 | GPR3 (0.55) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL18415783 | 0.94 | KDM4E (0.56) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL17676377 | 0.93 | GPR3 (0.53) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL17676359 | 0.93 | GPR3 (0.53) | GPR3KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL23373437 | 0.92 | KDM4E (0.58) | GPR3KDM4EMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7456424-B2 | Thin film transistors including indolocarbozoles | XEROX CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | GPR3 1112/4885KDM4E 2878/4885MAPT 196/4885 |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | GPR3 1112/4885KDM4E 2878/4885MAPT 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.