Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220714 | 0.98 | FDPS (0.46) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL24804995 | 0.88 | FDPS (0.53) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL29515049 | 0.88 | FDPS (0.53) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL11666395 | 0.88 | FDPS (0.53) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL16389287 | 0.81 | FDPS (0.45) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL8116639 | 0.80 | FDPS (0.50) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL5058596 | 0.80 | FDPS (0.50) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL31318443 | 0.80 | FDPS (0.50) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL156790 | 0.80 | FDPS (0.50) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 | |
| SCHEMBL6050306 | 0.79 | FDPS (0.42) | FDPSSLC6A2SLC6A3KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202995-B2 | Pharmaceutically acceptable salts of aporphine derivatives and carboxyl group-containing agents and methods for preparing the same | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2012-06-19 | — | — | US | disclosed |
| US-8093260-B2 | Aporphine derivatives and pharmaceutical use thereof | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20090318489-A1 | Aporphine compounds and pharmaceutical use thereof | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2009-12-24 | — | — | US | disclosed |
| US-20090318488-A1 | Pharmaceutically acceprable salts of aporphine compounds of carboxyl group-containing agents and methods for preparing the same | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318489-A1 | Aporphine compounds and pharmaceutical use thereof | IAPP, OPRL1, AGER | FDPS 4255/4885SLC6A2 194/4885SLC6A3 118/4885 |
| US-20090318488-A1 | Pharmaceutically acceprable salts of aporphine compounds of carboxyl group-containing agents and methods for preparing the same | IAPP, GPR119, AMY2A | FDPS 3127/4885SLC6A2 140/4885SLC6A3 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.