Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980357 | 0.84 | UCHL1 (0.36) | USP30ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL203375 | 0.81 | CYP3A4 (0.37) | USP30ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL2706060 | 0.81 | CYP3A4 (0.37) | USP30ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL16006323 | 0.78 | USP30 (0.43) | USP30ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL2706319 | 0.72 | CYP3A4 (0.48) | USP30CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL203309 | 0.72 | CYP3A4 (0.48) | USP30CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL204943 | 0.72 | CYP3A4 (0.48) | USP30CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15692856 | 0.72 | HPGDS (0.40) | USP30ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL15083853 | 0.72 | CYP3A4 (0.49) | USP30CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12048228 | 0.71 | HPGDS (0.41) | USP30ALDH1A1CYP3A4CYP2C9NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | USP30 1320/4885ALDH1A1 3957/4885TSHR 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.