Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980150 | 0.84 | USP30 (0.34) | UCHL1ALDH1A1USP30CYP3A4CYP2C9 | |
| SCHEMBL205434 | 0.79 | HPGDS (0.41) | UCHL1ALDH1A1CYP3A4CYP2C9NR1I2 | |
| SCHEMBL2707537 | 0.79 | HPGDS (0.41) | UCHL1ALDH1A1CYP3A4CYP2C9NR1I2 | |
| SCHEMBL10278871 | 0.79 | CYP3A4 (0.42) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL12048228 | 0.78 | HPGDS (0.41) | UCHL1ALDH1A1USP30CYP3A4CYP2C9 | |
| SCHEMBL45250 | 0.76 | UCHL1 (0.44) | UCHL1ALDH1A1USP30CYP3A4CYP2C9 | |
| SCHEMBL45280 | 0.76 | UCHL1 (0.44) | UCHL1ALDH1A1USP30CYP3A4CYP2C9 | |
| SCHEMBL2711186 | 0.76 | UCHL1 (0.44) | UCHL1ALDH1A1USP30CYP3A4CYP2C9 | |
| SCHEMBL21163741 | 0.75 | HPGDS (0.45) | ALDH1A1CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12139802 | 0.74 | HPGDS (0.51) | ALDH1A1CYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | UCHL1 2864/4885ALDH1A1 3957/4885USP30 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.