Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794414 | 0.98 | TSHR (0.63) | TSHRALDH1A1POLBCDC25BMAPT | |
| SCHEMBL28572995 | 0.85 | ALDH1A1 (0.58) | TSHRALDH1A1POLBCDC25BMAPT | |
| SCHEMBL437529 | 0.84 | ALDH1A1 (0.66) | TSHRALDH1A1POLBMAPTSRD5A2 | |
| SCHEMBL8662676 | 0.84 | ESR2 (0.61) | TSHRALDH1A1POLBMAPTSRD5A2 | |
| SCHEMBL1469205 | 0.83 | ALDH1A1 (0.54) | TSHRALDH1A1POLBSRD5A2HPGD | |
| SCHEMBL879015 | 0.83 | ALDH1A1 (0.54) | TSHRALDH1A1POLBHPGDCYP3A4 | |
| SCHEMBL29622719 | 0.83 | TSHR (0.65) | TSHRALDH1A1POLBCDC25BMAPT | |
| SCHEMBL51027 | 0.83 | TSHR (0.65) | TSHRALDH1A1POLBCDC25BMAPT | |
| Hydrochloric Acid SCHEMBL11879283 | 0.81 | ALDH1A1 (0.53) | TSHRALDH1A1POLBHPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL6778378 | 0.81 | TSHR (0.63) | TSHRALDH1A1POLBCDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773278-A | Quinazoline compound and application thereof in antivirus | 苏州大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114057917-A | Post-treatment ashless dispersant and preparation method thereof | 中国石油天然气股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-110508321-A | A kind of solid carbon-based Waugh type catalyst containing molybdenum heteropolyacid and its application | WENG FU GROUP CO LTD | 2019-11-29 | — | — | CN | claimed |
| EP-1725548-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF ASPARTIC ACETAL CASPASE INHIBITORS | VERTEX PHARMA (US) | 2015-01-14 | — | — | EP | claimed |
| US-20130066083-A1 | PROCESSES AND INTERMEDIATES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-03-14 | — | — | US | claimed |
| CN-1950364-B | Process and intermediates for preparing aspartate acetal caspase inhibitors | VERTEX PHARMA | 2011-06-08 | — | — | CN | claimed |
| US-7834200-B2 | Processes and intermediates | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-11-16 | — | — | US | claimed |
| US-7611692-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2009-11-03 | — | — | US | claimed |
| US-20090048429-A1 | Processes and intermediates | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-19 | — | — | US | claimed |
| CN-1950364-A | Process and intermediates for preparing aspartate acetal caspase inhibitors | VERTEX PHARMA (US) | 2007-04-18 | — | — | CN | claimed |
| EP-1725548-A2 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF ASPARTIC ACETAL CASPASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2006-11-29 | — | — | EP | claimed |
| US-20060110743-A1 | Drug evolution: drug design at hot spots | KONISHI YASUO | 2006-05-25 | — | — | US | claimed |
| US-20060020016-A1 | Processes and intermediates | VERTEX PHARMACEUTICALS INCORPORATED | 2006-01-26 | — | — | US | claimed |
| WO-2005090334-A2 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF ASPARTIC ACETAL CASPASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-09-29 | — | — | WO | claimed |
| WO-2002095393-A2 | DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2002-11-28 | — | — | WO | claimed |
| EP-0451094-B1 | Process for the production of pigments | CIBA GEIGY AG (CH) | 1995-02-01 | — | — | EP | claimed |
| US-5151129-A | Precipitation of pigments and coupling | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | claimed |
| EP-0451094-A1 | Process for the production of pigments | CIBA-GEIGY AG (CH) | 1991-10-09 | — | — | EP | claimed |
| EP-4673474-A2 | ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066083-A1 | PROCESSES AND INTERMEDIATES | CASP1, CASP3, CASP5 | TSHR 4859/4885ALDH1A1 378/4885POLB 1990/4885 |
| US-20090048429-A1 | Processes and intermediates | CASP1, CASP3, CASP5 | TSHR 4859/4885ALDH1A1 378/4885POLB 1990/4885 |
| US-20060020016-A1 | Processes and intermediates | CASP1, CASP3, CASP5 | TSHR 4859/4885ALDH1A1 378/4885POLB 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.