Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Monoxide SCHEMBL9988779 | 0.91 | ALDH1A1 (0.71) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| Formaldehyde SCHEMBL14837510 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1931125 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL420011 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5167895 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5169003 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL955977 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL95856 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25918085 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3394436 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987491-B2 | Rhenium complexes and their pharmaceutical use | SOCIETE DE COORDINATION DE RECHERCHES THERAPEUTIQUES (FR) | 2015-03-24 | — | — | US | disclosed |
| EP-2575800-B1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE. | COORDINATION DE RECH S THERAPEUTIQUES SOC D (FR) | 2015-01-14 | — | — | EP | disclosed |
| US-20130158109-A1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-06-20 | — | — | US | disclosed |
| EP-2392324-A1 | Rhenium complexes and their pharmaceutical use | SOCIETE DE COORDINATION DE RECHERCHES THERAPEUTIQUES (FR) | 2011-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158109-A1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE | REN, PKD1, KRAS | ALDH1A1 3976/4885MAPK1 1478/4885CYP1A2 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.