Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Monoxide SCHEMBL9987491 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| Formaldehyde SCHEMBL14837510 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL776647 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL95987 | 0.75 | ALDH1A1 (0.70) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL123612 | 0.75 | ALDH1A1 (0.70) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL1931125 | 0.74 | ALDH1A1 (0.78) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL420011 | 0.74 | ALDH1A1 (0.78) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL5143403 | 0.73 | ALDH1A1 (0.75) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL5169003 | 0.72 | ALDH1A1 (0.74) | ALDH1A1MAPK1FFAR1RAB9ANPC1 | |
| SCHEMBL5167895 | 0.72 | ALDH1A1 (0.74) | ALDH1A1MAPK1FFAR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987491-B2 | Rhenium complexes and their pharmaceutical use | SOCIETE DE COORDINATION DE RECHERCHES THERAPEUTIQUES (FR) | 2015-03-24 | — | — | US | disclosed |
| EP-2575800-B1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE. | COORDINATION DE RECH S THERAPEUTIQUES SOC D (FR) | 2015-01-14 | — | — | EP | disclosed |
| US-20130158109-A1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-06-20 | — | — | US | disclosed |
| EP-2392324-A1 | Rhenium complexes and their pharmaceutical use | SOCIETE DE COORDINATION DE RECHERCHES THERAPEUTIQUES (FR) | 2011-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158109-A1 | RHENIUM COMPLEXES AND THEIR PHARMACEUTICAL USE | REN, PKD1, KRAS | ALDH1A1 3976/4885MAPK1 1478/4885FFAR1 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.