Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985521 | 0.92 | MAPT (0.57) | TDP1L3MBTL1POLBMAPTKMT2A | |
| SCHEMBL9985257 | 0.90 | MAPT (0.48) | TDP1L3MBTL1POLBMAPTKMT2A | |
| SCHEMBL9987376 | 0.87 | TDP1 (0.48) | TDP1L3MBTL1POLBMAPTSERPINE1 | |
| SCHEMBL9988152 | 0.86 | TDP1 (0.47) | TDP1L3MBTL1POLBMAPTSERPINE1 | |
| SCHEMBL9984259 | 0.85 | ALDH1A1 (0.50) | TDP1L3MBTL1POLBMAPTKMT2A | |
| SCHEMBL9987975 | 0.85 | FLT3 (0.46) | TDP1MAPTSERPINE1KMT2AMEN1 | |
| SCHEMBL9987584 | 0.85 | BRD4 (0.51) | TDP1L3MBTL1POLBMAPTSERPINE1 | |
| SCHEMBL9983804 | 0.84 | SYK (0.41) | L3MBTL1MAPT | |
| SCHEMBL21643974 | 0.84 | MAPT (0.47) | TDP1POLBMAPTKMT2AMEN1 | |
| SCHEMBL9985022 | 0.84 | FGFR4 (0.42) | L3MBTL1POLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |