Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988138 | 1.00 | SIGMAR1 (0.50) | SIGMAR1HTR2CALDH1A1HSD11B1DRD2 | |
| SCHEMBL272499 | 0.85 | SIGMAR1 (0.52) | SIGMAR1HTR2CALDH1A1HSD11B1DRD2 | |
| SCHEMBL15510871 | 0.85 | SIGMAR1 (0.43) | SIGMAR1HTR2CALDH1A1HSD11B1DRD2 | |
| SCHEMBL15510873 | 0.85 | SIGMAR1 (0.43) | SIGMAR1HTR2CALDH1A1HSD11B1DRD2 | |
| SCHEMBL11590574 | 0.85 | SIGMAR1 (0.43) | SIGMAR1HTR2CALDH1A1HSD11B1DRD2 | |
| SCHEMBL360448 | 0.83 | ACMSD (0.47) | SIGMAR1HTR2CALDH1A1 | |
| SCHEMBL191429 | 0.81 | ACMSD (0.49) | SIGMAR1HTR2C | |
| SCHEMBL8380044 | 0.81 | ACMSD (0.49) | SIGMAR1HTR2C | |
| SCHEMBL28554683 | 0.80 | ALDH1A1 (0.50) | SIGMAR1HTR2CALDH1A1 | |
| SCHEMBL1109740 | 0.79 | ACMSD (0.47) | SIGMAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397509-A1 | Functionalized materials by catalyzed carbene copolymerization | Stichting Dutch Polymer Institute (NL) | 2011-12-21 | — | — | EP | disclosed |