Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | RPA1 | P27694 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 4/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989046 | 0.91 | TP53 (0.50) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9989355 | 0.89 | MALT1 (0.62) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9989126 | 0.85 | RXRA (0.55) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9989050 | 0.85 | CCKAR (0.58) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988492 | 0.85 | MALT1 (0.55) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988340 | 0.84 | RXRA (0.59) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988534 | 0.84 | MALT1 (0.55) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988359 | 0.84 | MALT1 (0.67) | MALT1RXRARXRBRXRGPTGS2 | |
| SCHEMBL9988397 | 0.84 | CACNA1G (0.56) | MALT1RXRARXRBRXRGPTGS2 | |
| SCHEMBL9989546 | 0.84 | MALT1 (0.55) | MALT1RXRARXRBRXRGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |