Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988308 | 0.91 | MALT1 (0.55) | TP53ALDH1A1MAPTRXRARXRB | |
| SCHEMBL9989656 | 0.89 | MALT1 (0.53) | TP53ALDH1A1MAPTRXRARXRB | |
| SCHEMBL9988522 | 0.88 | MALT1 (0.50) | RXRARXRBRXRGMALT1LMNA | |
| SCHEMBL9990141 | 0.88 | RXRA (0.51) | TP53MAPTRXRARXRBRXRG | |
| SCHEMBL9989144 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1MAPTMALT1LMNAKMT2A | |
| SCHEMBL9990096 | 0.86 | LMNA (0.47) | TP53ALDH1A1RXRARXRBRXRG | |
| SCHEMBL9990250 | 0.86 | RXRA (0.51) | TP53MAPTRXRARXRBRXRG | |
| SCHEMBL9988515 | 0.86 | MC4R (0.53) | TP53RXRARXRBRXRGMALT1 | |
| SCHEMBL9988490 | 0.86 | LMNA (0.49) | TP53ALDH1A1MAPTRXRARXRB | |
| SCHEMBL9988891 | 0.85 | RXRA (0.49) | TP53RXRARXRBRXRGMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |