Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MDH1 | P40925 | 1/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223565 | 0.82 | HRH3 (0.71) | MEN1KMT2AL3MBTL1GPR183ALDH1A1 | |
| SCHEMBL9987696 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL9988381 | 0.81 | HTR7 (0.66) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1044315 | 0.80 | KCNH2 (0.58) | MEN1KMT2AGPR183ALDH1A1POLB | |
| SCHEMBL10254050 | 0.79 | MEN1 (0.60) | MEN1KMT2AL3MBTL1GPR183ALDH1A1 | |
| SCHEMBL22016055 | 0.77 | MEN1 (0.60) | MEN1KMT2AGPR183ALDH1A1HRH3 | |
| SCHEMBL22131068 | 0.77 | MEN1 (0.60) | MEN1KMT2AGPR183ALDH1A1HRH3 | |
| SCHEMBL5066438 | 0.76 | MDH1 (0.66) | MEN1KMT2AGPR183SMN1; SMN2ALDH1A1 | |
| SCHEMBL17938599 | 0.76 | ALDH1A1 (0.74) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31587154 | 0.76 | MEN1 (0.88) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383631-B2 | 1,6-disubstituted-3-amino-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-C]pyridin-7-one compounds and preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-26 | — | — | US | disclosed |
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, THPO, PLEC | MEN1 620/4885KMT2A 2707/4885L3MBTL1 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.