Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793166 | 0.85 | NCF1 (0.46) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL12072936 | 0.85 | HTR1A (0.51) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL5740977 | 0.83 | HTR1A (0.44) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL13547748 | 0.83 | ALDH1A1 (0.45) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL27876384 | 0.82 | NCF1 (0.55) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL29310423 | 0.81 | HTR1A (0.43) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL27372168 | 0.81 | HTR1A (0.43) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL24123988 | 0.80 | ADRB2 (0.48) | NCF1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL8710759 | 0.77 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL29505669 | 0.77 | NCF1 (0.87) | NCF1MAPTKDM4EHTR1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105363-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |