Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 9/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 9/20 | 0.46 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989142 | 0.86 | CA1 (0.48) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988456 | 0.86 | SLC16A3 (0.53) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9989540 | 0.84 | MALT1 (0.52) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988484 | 0.84 | MALT1 (0.47) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9989408 | 0.80 | DRD4 (0.51) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988534 | 0.80 | MALT1 (0.55) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9990073 | 0.80 | RXRA (0.48) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9989046 | 0.80 | TP53 (0.50) | SLC16A3SLC16A1MCTS1MALT1RXRA | |
| SCHEMBL9990141 | 0.79 | RXRA (0.51) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988387 | 0.79 | DRD4 (0.49) | CA1CA2CA9PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |