Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988979 | 0.89 | ADORA2A (0.43) | SMN1; SMN2ALDH1A1MALT1MAPTKDM4E | |
| SCHEMBL9988522 | 0.89 | MALT1 (0.50) | SMN1; SMN2MALT1P2RX7NTRK1LMNA | |
| SCHEMBL9988443 | 0.88 | NAMPT (0.44) | ALDH1A1MALT1MAPTGAALMNA | |
| SCHEMBL9989046 | 0.87 | TP53 (0.50) | ALDH1A1MALT1MAPTNTRK1LMNA | |
| SCHEMBL9988828 | 0.87 | MALT1 (0.45) | SMN1; SMN2MALT1MAPTS1PR3LMNA | |
| SCHEMBL9988868 | 0.85 | MALT1 (0.44) | MALT1MAPTLMNAHPGDPOLB | |
| SCHEMBL9988364 | 0.85 | MALT1 (0.49) | MALT1HPGDKMT2ATHRB | |
| SCHEMBL9989719 | 0.82 | HPGD (0.48) | SMN1; SMN2ALDH1A1MALT1P2RX7MAPT | |
| SCHEMBL9988469 | 0.81 | RAB9A (0.40) | SMN1; SMN2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL9988617 | 0.80 | MALT1 (0.43) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |