Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.46 |
| ▸ | RXRG | P48443 | 4/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.45 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989849 | 0.94 | MALT1 (0.53) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9988569 | 0.93 | MALT1 (0.51) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9989579 | 0.91 | RXRA (0.52) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9990250 | 0.90 | RXRA (0.51) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9988395 | 0.86 | MALT1 (0.55) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988933 | 0.84 | CACNA1G (0.58) | MALT1RXRARXRBRXRGP2RX7 | |
| SCHEMBL9989595 | 0.84 | RXRA (0.51) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9990146 | 0.83 | RXRA (0.50) | MALT1RXRARXRBRXRGSLC16A3 | |
| SCHEMBL9988310 | 0.83 | CACNA1G (0.50) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989306 | 0.82 | RXRA (0.52) | MALT1RXRARXRBRXRGSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |