Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.58 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.47 |
| ▸ | RXRB | P28702 | 4/20 | 0.47 |
| ▸ | RXRG | P48443 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988310 | 0.93 | CACNA1G (0.50) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9989849 | 0.91 | MALT1 (0.53) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988512 | 0.89 | MALT1 (0.57) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9989837 | 0.89 | P2RX7 (0.48) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988663 | 0.89 | PTGS2 (0.48) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9989721 | 0.88 | MALT1 (0.56) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988569 | 0.84 | MALT1 (0.51) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988565 | 0.84 | MALT1 (0.51) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988397 | 0.84 | CACNA1G (0.56) | CACNA1GCACNA1HMALT1RXRARXRB | |
| SCHEMBL9988840 | 0.84 | MALT1 (0.52) | CACNA1GCACNA1HMALT1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |