Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27103091 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL776647 | 0.87 | ALDH1A1 (1.00) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL25918085 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL23051154 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL27103064 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22755712 | 0.78 | NPC1 (0.57) | ALDH1A1MAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5171094 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL27103048 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPK1MTNR1AMTNR1BMAOA | |
| SCHEMBL575835 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL11661294 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPK1MTNR1AMTNR1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | disclosed |
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-02-07 | — | — | US | disclosed |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-11 | — | — | US | disclosed |
| US-8084644-B2 | Agricultural pesticide; Wide variety of compounds, for example phenyl N-phenyl-3-(phenylthio)thioacrylimidate; formula X-CH=CH-C(-Y)=N-Z where X, Y and Z are variable | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-8084644-B2 | Agricultural pesticide; Wide variety of compounds, for example phenyl N-phenyl-3-(phenylthio)thioacrylimidate; formula X-CH=CH-C(-Y)=N-Z where X, Y and Z are variable | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885MAPK1 3885/4885MTNR1A 3783/4885 |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | NDUFB7, NDUFB1, NDUFB3 | ALDH1A1 638/4885MAPK1 4737/4885MTNR1A 1052/4885 |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885MAPK1 3885/4885MTNR1A 3783/4885 |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | DBH, DDT, CBR3 | ALDH1A1 985/4885MAPK1 3708/4885MTNR1A 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.