Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.66 |
| ▸ | RXRB | P28702 | 7/20 | 0.66 |
| ▸ | RXRG | P48443 | 7/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.48 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.48 |
| ▸ | CCKAR | P32238 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999143 | 0.85 | RXRA (0.69) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL9695677 | 0.80 | RXRA (0.74) | RXRARXRBRXRGPTGS2ALOX5 | |
| Hydrochloric Acid SCHEMBL9466114 | 0.80 | RXRA (0.68) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL5393447 | 0.79 | RXRA (0.84) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL23645857 | 0.78 | PTGS2 (0.56) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL23645909 | 0.77 | ALOX5 (0.58) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL14445463 | 0.74 | RXRA (0.78) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL4014121 | 0.74 | CCKAR (0.71) | PTGS2RPA1CA1CA2CA9 | |
| SCHEMBL9989355 | 0.73 | MALT1 (0.62) | RXRARXRBRXRGPTGS2ALOX5 | |
| SCHEMBL9989245 | 0.72 | MAPT (0.52) | RXRARXRBRXRGPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |