Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988523 | 0.89 | ALOX5 (0.54) | FKBP1APTGS2RXRARXRBRXRG | |
| SCHEMBL9999143 | 0.84 | RXRA (0.69) | PTGS2RXRARXRBRXRGALOX5 | |
| SCHEMBL9988350 | 0.80 | ALOX5 (0.56) | PTGS2RXRARXRBRXRGALOX5 | |
| SCHEMBL9988389 | 0.80 | ALOX5 (0.56) | PTGS2RXRARXRBRXRGALOX5 | |
| SCHEMBL9990141 | 0.78 | RXRA (0.51) | MAPTPTGS2RXRARXRBRXRG | |
| SCHEMBL9988533 | 0.77 | LMNA (0.49) | MAPTPTGS2RXRARXRBRXRG | |
| SCHEMBL9988576 | 0.77 | LMNA (0.47) | MAPTPTGS2RXRARXRBRXRG | |
| SCHEMBL9989656 | 0.77 | MALT1 (0.53) | MAPTPTGS2RXRARXRBRXRG | |
| SCHEMBL9988966 | 0.77 | MAPT (0.51) | MAPTPTGS2RXRARXRBRXRG | |
| SCHEMBL9990096 | 0.76 | LMNA (0.47) | PTGS2RXRARXRBRXRGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |