Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.45 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988387 | 0.92 | DRD4 (0.49) | DRD4SMN1; SMN2CA1CA2CA9 | |
| SCHEMBL9988533 | 0.92 | LMNA (0.49) | DRD4SMN1; SMN2KDM4EPOLBALOX5 | |
| SCHEMBL9990127 | 0.87 | CA1 (0.44) | DRD4CA1CA2CA9SLC16A3 | |
| SCHEMBL9988671 | 0.86 | ALOX5 (0.48) | ALOX5MAPTRXRARXRBRXRG | |
| SCHEMBL9989252 | 0.83 | NPC1 (0.53) | SMN1; SMN2CA1CA2CA9ALOX15 | |
| SCHEMBL9989142 | 0.82 | CA1 (0.48) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988456 | 0.81 | SLC16A3 (0.53) | SMN1; SMN2CA1CA2CA9SLC16A3 | |
| SCHEMBL9988915 | 0.80 | CA1 (0.47) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9989540 | 0.80 | MALT1 (0.52) | CA1CA2CA9SLC16A3SLC16A1 | |
| SCHEMBL9988702 | 0.79 | PTGS2 (0.58) | KDM4EPOLBALOX5RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |