Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245159 | 0.94 | LMNA (0.45) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16672925 | 0.84 | NPC1 (0.50) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5157613 | 0.83 | TSHR (0.52) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL6883415 | 0.82 | LMNA (0.39) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL28547523 | 0.81 | SLC6A3 (0.57) | LMNAHSD17B10SLC6A3ESR1ESR2 | |
| SCHEMBL16672527 | 0.79 | MAPT (0.56) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL9989140 | 0.79 | ESR1 (0.49) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16623989 | 0.78 | PTGS2 (0.50) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16674880 | 0.78 | HSD17B10 (0.63) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL28860170 | 0.78 | MEN1 (0.57) | LMNAKDM4EHSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |