Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665890 | 0.87 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL2797501 | 0.85 | ALDH1A1 (0.53) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL9263634 | 0.84 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL30850062 | 0.82 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL11589528 | 0.82 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL68677 | 0.82 | PTGS2 (0.55) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3628841 | 0.81 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| Benzene SCHEMBL28173619 | 0.81 | PTGS2 (0.58) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL10924111 | 0.81 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL16245159 | 0.81 | LMNA (0.45) | PTGS2KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099723-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099723-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | FASN, ACACA, FABP4 | PTGS2 80/4885KDM4E 2493/4885HSD17B10 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.