Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.51 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | DDT | P30046 | 2/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988509 | 0.92 | MALT1 (0.50) | MALT1ALOX5RXRARXRBRXRG | |
| SCHEMBL9988479 | 0.91 | MALT1 (0.49) | ILKMALT1RXRARXRBRXRG | |
| SCHEMBL9988840 | 0.91 | MALT1 (0.52) | MALT1ALOX5RXRARXRBRXRG | |
| SCHEMBL9989423 | 0.90 | MALT1 (0.48) | ILKMALT1ALOX5RXRARXRB | |
| SCHEMBL9988720 | 0.90 | EPHX2 (0.46) | ILKMALT1ALOX5EPHX2RXRA | |
| SCHEMBL9988866 | 0.89 | MALT1 (0.49) | MALT1ALOX5RXRARXRBRXRG | |
| SCHEMBL9989581 | 0.89 | ILK (0.49) | ILKMALT1ALOX5EPHX2RXRA | |
| SCHEMBL9988903 | 0.88 | RXRA (0.48) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989011 | 0.88 | RXRA (0.48) | MALT1ALOX5RXRARXRBRXRG | |
| SCHEMBL9988806 | 0.88 | MALT1 (0.47) | ILKMALT1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |