Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989011 | 0.91 | RXRA (0.48) | PTGS2MALT1ALOX5PTGS1TP53 | |
| SCHEMBL9988509 | 0.90 | MALT1 (0.50) | MALT1ALOX5PTGS1TP53LMNA | |
| SCHEMBL9988467 | 0.90 | MALT1 (0.45) | MALT1SLC5A1ALOX5PTGS1TP53 | |
| SCHEMBL9989173 | 0.90 | ILK (0.51) | EPHX2PTGS2MALT1SLC5A1ALOX5 | |
| SCHEMBL9988461 | 0.89 | PTGS2 (0.45) | EPHX2PTGS2MALT1SLC5A1ALOX5 | |
| SCHEMBL9988479 | 0.88 | MALT1 (0.49) | MALT1ILKTP53LMNARXFP1 | |
| SCHEMBL9988840 | 0.88 | MALT1 (0.52) | MALT1ALOX5PTGS1TP53RXFP1 | |
| SCHEMBL9988908 | 0.88 | MALT1 (0.46) | EPHX2PTGS2MALT1SLC5A1ALOX5 | |
| SCHEMBL9989423 | 0.88 | MALT1 (0.48) | MALT1ALOX5ILKTP53LMNA | |
| SCHEMBL9988828 | 0.87 | MALT1 (0.45) | MALT1ALOX5TP53LMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |