Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030430 | 0.83 | MAPT (0.55) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| Hydrochloric Acid SCHEMBL5252883 | 0.81 | MAPT (0.53) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| SCHEMBL2202827 | 0.77 | CHRM3 (0.47) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| SCHEMBL9989235 | 0.74 | MAPT (0.40) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| SCHEMBL9989241 | 0.73 | MAPT (0.39) | MAPTKMT2ACYP3A4 | |
| SCHEMBL17596757 | 0.71 | CYP3A4 (0.47) | LMNACYP3A4TDP1 | |
| SCHEMBL2201632 | 0.70 | KDM4E (0.43) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| SCHEMBL9295790 | 0.70 | CHRM3 (0.59) | CHRM3KCNH2CHRM2CHRM1LMNA | |
| SCHEMBL10552 | 0.70 | OPRM1 (0.52) | LMNAOPRM1OPRD1HTT | |
| SCHEMBL20607354 | 0.69 | OPRM1 (0.66) | CHRM3KCNH2CHRM2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |