Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845811 | 0.80 | MAPT (0.55) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL2202821 | 0.77 | MAPT (0.43) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL9989235 | 0.73 | MAPT (0.40) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL10483819 | 0.71 | ALOX15 (0.47) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL11220671 | 0.70 | KIF11 (0.50) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL5268840 | 0.70 | SLC6A2 (0.57) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL407788 | 0.70 | SLC6A2 (0.57) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL407787 | 0.70 | SLC6A2 (0.57) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| SCHEMBL8759 | 0.69 | SLC6A2 (0.56) | MAPTKMT2ACYP3A4CYP1A2RECQL | |
| Hydrochloric Acid SCHEMBL28585466 | 0.69 | SLC6A2 (0.55) | MAPTKMT2ACYP3A4CYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |